Antitussive activity of iodo-resiniferatoxin in guinea pigs
نویسندگان
چکیده
منابع مشابه
Antitussive activity of iodo-resiniferatoxin in guinea pigs.
BACKGROUND Iodo-resiniferatoxin (I-RTX) has recently been described as an ultra potent antagonist of the transient receptor potential vanilloid-1 (TRPV1). METHODS The ability of I-RTX to inhibit cough induced by inhalation of two putative TRPV1 stimulants (capsaicin and citric acid) was tested in non-anaesthetised guinea pigs. RESULTS Pretreatment with I-RTX either intraperitoneally (0.03-0...
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ژورنال
عنوان ژورنال: Thorax
سال: 2004
ISSN: 0040-6376
DOI: 10.1136/thx.2003.012930